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Every answer shows how strong the evidence is.

Each claim is graded A to D on the GRADE scale and linked to its PubMed record. Weak evidence is labelled weak.

One answer, as Supercell showed it

Evidence grade: C (low certainty, guideline consensus and one large trial)

Sources

Limit

The intervals rest on expert consensus, not on trials comparing schedules.

What the grades mean

A, high
Well-run randomised trials with consistent results.
B, moderate
Solid trials with some limits, or trials together with observational studies.
C, low
Few trials, weak methods, or results carried over from laboratory and animal studies.
D, very low
Case reports, theory, or no published clinical studies.

The method

PICO
Each question is broken into population, intervention, comparison and outcome before the search.
Three lenses
Evidence is scored separately for health and disease, longevity and performance.
Citations
Claims link to their sources by PubMed ID, so you can read them yourself.

What it does not do

  • It supports decisions. It does not make them.
  • Drafts stay drafts until a physician signs them.
  • Supercell is not a medical device.

See it with your own cases

We walk you through it on cases like yours.