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A 58-year-old man on a hormone replacement protocol asks how often his blood counts and prostate marker should be checked. What does the evidence support?

Supercell

Supercell is thinking…

Blood counts. Check haematocrit before starting, at 3 to 6 months, at 12 months and then yearly, and pause the therapy if it rises above 54% (Bhasin et al., 2018, PMID 29562364).

Prostate marker. If he chooses prostate screening, check PSA before starting and at 3 to 12 months, then on the usual screening schedule. Refer to urology for a rise of more than 1.4 ng/mL within a year or a confirmed level above 4.0 ng/mL (Bhasin et al., 2018).

Safety. In men aged 45 to 80 at high cardiovascular risk, the therapy was non-inferior to placebo for major cardiovascular events. Atrial fibrillation, acute kidney injury and pulmonary embolism were more frequent (Lincoff et al., 2023, PMID 37326322).

For this patient. At 58 he is in the guideline's age range for PSA checks. Take a baseline haematocrit and PSA if none exists, then follow the schedule above.

Limit. The intervals rest on expert consensus, not on trials comparing schedules.

GRADE CConfidence: low

2 sources

Bhasin et al., 2018 · PMID 29562364
Lincoff et al., 2023 · PMID 37326322

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A 58-year-old man on a hormone replacement protocol asks how often his blood counts and prostate marker should be checked. What does the evidence support?

Supercell

Supercell is thinking…

Blood counts. Check haematocrit before starting, at 3 to 6 months, at 12 months and then yearly, and pause the therapy if it rises above 54% (Bhasin et al., 2018, PMID 29562364).

For this patient. At 58 he is in the guideline's age range for PSA checks. Take a baseline haematocrit and PSA if none exists, then follow the schedule above.

Limit. The intervals rest on expert consensus, not on trials comparing schedules.

GRADE CConfidence: low

2 sources

Bhasin et al., 2018 · PMID 29562364
Lincoff et al., 2023 · PMID 37326322

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Monitoring on a hormone replacement protocol
Thyroid labs before a weight protocol
Washout between two courses
Iron studies in a tired runner
Sleep and recovery: what to ask first
A 58-year-old man on a hormone replacement protocol asks how often his blood counts and prostate marker should be checked. What does the evidence support?
Supercell
Supercell is thinking…
Blood counts. Check haematocrit before starting, at 3 to 6 months, at 12 months and then yearly, and pause the therapy if it rises above 54% (Bhasin et al., 2018, PMID 29562364).
Prostate marker. If he chooses prostate screening, check PSA before starting and at 3 to 12 months, then on the usual screening schedule. Refer to urology for a rise of more than 1.4 ng/mL within a year or a confirmed level above 4.0 ng/mL (Bhasin et al., 2018).
Safety. In men aged 45 to 80 at high cardiovascular risk, the therapy was non-inferior to placebo for major cardiovascular events. Atrial fibrillation, acute kidney injury and pulmonary embolism were more frequent (Lincoff et al., 2023, PMID 37326322).
For this patient. At 58 he is in the guideline's age range for PSA checks. Take a baseline haematocrit and PSA if none exists, then follow the schedule above.
Limit. The intervals rest on expert consensus, not on trials comparing schedules.
GRADE CConfidence: low
2 sources
Bhasin et al., 2018 · PMID 29562364
Lincoff et al., 2023 · PMID 37326322
Ask Supercell anything clinical…
Draft for your review. Not medical advice.
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A 58-year-old man on a hormone replacement protocol asks how often his blood counts and prostate marker should be checked. What does the evidence support?
Supercell
Supercell is thinking…
Blood counts. Check haematocrit before starting, at 3 to 6 months, at 12 months and then yearly, and pause the therapy if it rises above 54% (Bhasin et al., 2018, PMID 29562364).
Prostate marker. If he chooses prostate screening, check PSA before starting and at 3 to 12 months, then on the usual screening schedule. Refer to urology for a rise of more than 1.4 ng/mL within a year or a confirmed level above 4.0 ng/mL (Bhasin et al., 2018).
Safety. In men aged 45 to 80 at high cardiovascular risk, the therapy was non-inferior to placebo for major cardiovascular events. Atrial fibrillation, acute kidney injury and pulmonary embolism were more frequent (Lincoff et al., 2023, PMID 37326322).
For this patient. At 58 he is in the guideline's age range for PSA checks. Take a baseline haematocrit and PSA if none exists, then follow the schedule above.
Limit. The intervals rest on expert consensus, not on trials comparing schedules.
GRADE CConfidence: low
2 sources
Bhasin et al., 2018 · PMID 29562364
Lincoff et al., 2023 · PMID 37326322
Ask Supercell anything clinical…
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Eleanor Pena
Signed · v3
47 · F · Recovery plan · Approved by Dr. Robin Alex on Oct 7, 2026
Download PDFRevise
Signature
Approved by Dr. Robin Alex on Oct 7, 2026, 05:47
I reviewed every section and approve this protocol for this patient.
Patients and the PDF show: Signed off by the Supercell team.
Content SHA-2569f2c4e81a07d3b56c1e8f4a92d70b3c5e6a1f08d4b27c9e3a5f6d81b0c4e7a29
Confidence
Moderate68/100
Screening complete and accepted
Recent bloodwork confirmed
Evidence mostly from animal studies
Versions
v3Oct 7, 2026Latest
v2Sep 30, 2026Superseded
v1Sep 29, 2026Superseded
Clinical impression
Ready
Low energy for three months and poor recovery after training in a 47-year-old woman with no current medicines. Sleep and diet reviewed; no red flags at intake.
Recommended compounds
Ready
Recovery peptide A first for tissue support; Recovery peptide B second as a complementary agent.
Recovery peptide A
GRADE C
Animal data; no completed human trials.
A short peptide studied for tendon, muscle and gut-lining repair in animal models.
Why it fits
Starts low for a first course
Risks the schedule mitigates
Injection-site redness: rotate sites
Recovery peptide B
GRADE C
Animal and early human data.
A synthetic fragment of a repair protein that supports cell migration in injured tissue.
Why it fits
Complements the first compound by a different mechanism
Risks the schedule mitigates
Tiredness at higher doses: keep to the schedule
Dosing schedule
Ready
Weeks 1 to 4, then review at the follow-up visit.
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Eleanor Pena
Signed · v3
47 · F · Recovery plan · Approved by Dr. Robin Alex on Oct 7, 2026
Download PDFRevise
Clinical impression
Ready
Low energy for three months and poor recovery after training in a 47-year-old woman with no current medicines. Sleep and diet reviewed; no red flags at intake.
Recommended compounds
Ready
Recovery peptide A first for tissue support; Recovery peptide B second as a complementary agent.
Recovery peptide A
GRADE C
Animal data; no completed human trials.
A short peptide studied for tendon, muscle and gut-lining repair in animal models.
Why it fits
Starts low for a first course
Risks the schedule mitigates
Injection-site redness: rotate sites
Recovery peptide B
GRADE C
Animal and early human data.
A synthetic fragment of a repair protein that supports cell migration in injured tissue.
Why it fits
Complements the first compound by a different mechanism
Risks the schedule mitigates
Tiredness at higher doses: keep to the schedule
Dosing schedule
Ready
Weeks 1 to 4, then review at the follow-up visit.
Draft and sign
Draft the protocol from the intake, review it and sign.
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1
Your vial
The peptide amount is printed on the vial label.
Peptide vial quantity
5 mg10 mg15 mgCustom
−5 mg+
2
Amount per injection
How much peptide one injection should give.
Desired dose per injection
50 mcg100 mcg250 mcg500 mcgCustom
−250 mcg+= 0.25 mg
3
Bacteriostatic water
More water makes each unit carry less peptide. It changes the concentration, not the dose.
Use sliderEnter exact amount
2 ml
1 ml2 ml3 mlmost vials5 ml7 ml
Concentration: 2.5 mg/ml
4
Syringe
Pick the insulin syringe you'll draw with.
Syringe volume
0.3 ml · 30 units0.5 ml · 50 units1 ml · 100 unitsCustom
Result Checked by the server
Draw syringe to
10 units
0.1 ml on a 1 ml (100-unit) syringe
Per draw250 mcg
Vial holds20 draws
Concentration2.5 mg/ml
Know when this vial runs out
Every day5× / week3× / weekWeekly
Lasts about 2.9 weeks: mixed today, it runs out around 28 Oct.
Mixed vials keep about 3 weeks at 4 °C.
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Draw syringe to
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0.1 ml on a 1 ml (100-unit) syringe
Per draw250 mcg
Vial holds20 draws
Concentration2.5 mg/ml
Know when this vial runs out
Every day5× / week3× / weekWeekly
Lasts about 2.9 weeks: mixed today, it runs out around 28 Oct.
Mixed vials keep about 3 weeks at 4 °C.
1
Your vial
The peptide amount is printed on the vial label.
Peptide vial quantity
5 mg10 mg15 mgCustom
−5 mg+
2
Amount per injection
How much peptide one injection should give.
Desired dose per injection
50 mcg100 mcg250 mcg500 mcgCustom
−250 mcg+= 0.25 mg
3
Bacteriostatic water
More water makes each unit carry less peptide. It changes the concentration, not the dose.
Use sliderEnter exact amount
2 ml
1 ml2 ml3 mlmost vials5 ml7 ml
Concentration: 2.5 mg/ml
4
Syringe
Pick the insulin syringe you'll draw with.
Syringe volume
0.3 ml · 30 units0.5 ml · 50 units1 ml · 100 unitsCustom
Dose
Results in syringe units. The same inputs always give the same result.

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Monitoring on a hormone replacement protocol
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Washout between two courses
Iron studies in a tired runner
Sleep and recovery: what to ask first
A 58-year-old man on a hormone replacement protocol asks how often his blood counts and prostate marker should be checked. What does the evidence support?
Supercell
Supercell is thinking…
Blood counts. Check haematocrit before starting, at 3 to 6 months, at 12 months and then yearly, and pause the therapy if it rises above 54% (Bhasin et al., 2018, PMID 29562364).
Prostate marker. If he chooses prostate screening, check PSA before starting and at 3 to 12 months, then on the usual screening schedule. Refer to urology for a rise of more than 1.4 ng/mL within a year or a confirmed level above 4.0 ng/mL (Bhasin et al., 2018).
Safety. In men aged 45 to 80 at high cardiovascular risk, the therapy was non-inferior to placebo for major cardiovascular events. Atrial fibrillation, acute kidney injury and pulmonary embolism were more frequent (Lincoff et al., 2023, PMID 37326322).
For this patient. At 58 he is in the guideline's age range for PSA checks. Take a baseline haematocrit and PSA if none exists, then follow the schedule above.
Limit. The intervals rest on expert consensus, not on trials comparing schedules.
GRADE CConfidence: low
2 sources
Bhasin et al., 2018 · PMID 29562364
Lincoff et al., 2023 · PMID 37326322
Ask Supercell anything clinical…
Draft for your review. Not medical advice.
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A 58-year-old man on a hormone replacement protocol asks how often his blood counts and prostate marker should be checked. What does the evidence support?
Supercell
Supercell is thinking…
Blood counts. Check haematocrit before starting, at 3 to 6 months, at 12 months and then yearly, and pause the therapy if it rises above 54% (Bhasin et al., 2018, PMID 29562364).
Prostate marker. If he chooses prostate screening, check PSA before starting and at 3 to 12 months, then on the usual screening schedule. Refer to urology for a rise of more than 1.4 ng/mL within a year or a confirmed level above 4.0 ng/mL (Bhasin et al., 2018).
Safety. In men aged 45 to 80 at high cardiovascular risk, the therapy was non-inferior to placebo for major cardiovascular events. Atrial fibrillation, acute kidney injury and pulmonary embolism were more frequent (Lincoff et al., 2023, PMID 37326322).
For this patient. At 58 he is in the guideline's age range for PSA checks. Take a baseline haematocrit and PSA if none exists, then follow the schedule above.
Limit. The intervals rest on expert consensus, not on trials comparing schedules.
GRADE CConfidence: low
2 sources
Bhasin et al., 2018 · PMID 29562364
Lincoff et al., 2023 · PMID 37326322
Ask Supercell anything clinical…
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Aurora LongevityVersion 3
Recovery peptide A · Recovery peptide BSigned off by the Supercell team on October 7, 2026
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Aurora LongevityVersion 3
Recovery peptide A · Recovery peptide BSigned off by the Supercell team on October 7, 2026
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The work	The old way	With Supercell	Time back
Staying current on peptides	The old way: Evenings on PubMed and conference notes	With Supercell: Answers graded A to D, with PubMed sources	Time back: Hours a week back
Drafting a protocol	The old way: Templates and Word, retyping between five tools	With Supercell: A cited draft from the intake, ready to review and sign	Time back: 3 س to 12 د
Dosage and reconstitution	The old way: Spreadsheet formulas copied by hand	With Supercell: Syringe-unit math with the working shown	Time back: Same inputs, same result
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A 58-year-old man on a hormone replacement protocol asks how often his blood counts and prostate marker should be checked. What does the evidence support?

Supercell

Supercell is thinking…

Blood counts. Check haematocrit before starting, at 3 to 6 months, at 12 months and then yearly, and pause the therapy if it rises above 54% (Bhasin et al., 2018, PMID 29562364).

For this patient. At 58 he is in the guideline's age range for PSA checks. Take a baseline haematocrit and PSA if none exists, then follow the schedule above.

Limit. The intervals rest on expert consensus, not on trials comparing schedules.

GRADE CConfidence: low

2 sources

Bhasin et al., 2018 · PMID 29562364
Lincoff et al., 2023 · PMID 37326322

Ask Supercell anything clinical…

Draft for your review. Not medical advice.

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Search patients…Invite patientNew protocol

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A 58-year-old man on a hormone replacement protocol asks how often his blood counts and prostate marker should be checked. What does the evidence support?

Supercell

Supercell is thinking…

Blood counts. Check haematocrit before starting, at 3 to 6 months, at 12 months and then yearly, and pause the therapy if it rises above 54% (Bhasin et al., 2018, PMID 29562364).

For this patient. At 58 he is in the guideline's age range for PSA checks. Take a baseline haematocrit and PSA if none exists, then follow the schedule above.

Limit. The intervals rest on expert consensus, not on trials comparing schedules.

GRADE CConfidence: low

2 sources

Bhasin et al., 2018 · PMID 29562364
Lincoff et al., 2023 · PMID 37326322

Ask Supercell anything clinical…

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Eleanor Pena

Signed · v3

47 · F · Recovery plan · Approved by Dr. Robin Alex on Oct 7, 2026

Download PDFRevise

Clinical impression

Ready

Low energy for three months and poor recovery after training in a 47-year-old woman with no current medicines. Sleep and diet reviewed; no red flags at intake.

Recommended compounds

Ready

Recovery peptide A first for tissue support; Recovery peptide B second as a complementary agent.

Recovery peptide A

GRADE C

Animal data; no completed human trials.

A short peptide studied for tendon, muscle and gut-lining repair in animal models.

Why it fits

Starts low for a first course

Risks the schedule mitigates

Injection-site redness: rotate sites

Recovery peptide B

GRADE C

Animal and early human data.

A synthetic fragment of a repair protein that supports cell migration in injured tissue.

Why it fits

Complements the first compound by a different mechanism

Risks the schedule mitigates

Tiredness at higher doses: keep to the schedule

Dosing schedule

Ready

Weeks 1 to 4, then review at the follow-up visit.

Protocols

Search patients…Invite patientNew protocol

All protocols

Eleanor Pena

Signed · v3

47 · F · Recovery plan · Approved by Dr. Robin Alex on Oct 7, 2026

Download PDFRevise

Clinical impression

Ready

Low energy for three months and poor recovery after training in a 47-year-old woman with no current medicines. Sleep and diet reviewed; no red flags at intake.

Recommended compounds

Ready

Recovery peptide A first for tissue support; Recovery peptide B second as a complementary agent.

Recovery peptide A

GRADE C

Animal data; no completed human trials.

A short peptide studied for tendon, muscle and gut-lining repair in animal models.

Why it fits

Starts low for a first course

Risks the schedule mitigates

Injection-site redness: rotate sites

Recovery peptide B

GRADE C

Animal and early human data.

A synthetic fragment of a repair protein that supports cell migration in injured tissue.

Why it fits

Complements the first compound by a different mechanism

Risks the schedule mitigates

Tiredness at higher doses: keep to the schedule

Dosing schedule

Ready

Weeks 1 to 4, then review at the follow-up visit.

Reconstitution and dosing math. No AI involved.

Results in syringe units

More about Dosage Calculator

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Units to draw from a vial, or clicks on a pen

VialsPens

BeginnerAdvanced

Your vial

The peptide amount is printed on the vial label.

Peptide vial quantity

5 mg10 mg15 mgCustom

−5 mg+

Amount per injection

How much peptide one injection should give.

Desired dose per injection

50 mcg100 mcg250 mcg500 mcgCustom

−250 mcg+= 0.25 mg

Bacteriostatic water

More water makes each unit carry less peptide. It changes the concentration, not the dose.

Use sliderEnter exact amount

2 ml

1 ml2 ml3 mlmost vials5 ml7 ml

Concentration: 2.5 mg/ml

Syringe

Pick the insulin syringe you'll draw with.

Syringe volume

0.3 ml · 30 units0.5 ml · 50 units1 ml · 100 unitsCustom

Result Checked by the server

Draw syringe to

10 units

0.1 ml on a 1 ml (100-unit) syringe

Per draw250 mcg

Vial holds20 draws

Concentration2.5 mg/ml

Know when this vial runs out

Every day5× / week3× / weekWeekly

Lasts about 2.9 weeks: mixed today, it runs out around 28 Oct.

Mixed vials keep about 3 weeks at 4 °C.

Calculators

Search patients…Invite patientNew protocol

All calculators

Dosage calculator

Units to draw from a vial, or clicks on a pen

VialsPens

BeginnerAdvanced

Result Checked by the server

Draw syringe to

10 units

0.1 ml on a 1 ml (100-unit) syringe

Per draw250 mcg

Vial holds20 draws

Concentration2.5 mg/ml

Know when this vial runs out

Every day5× / week3× / weekWeekly

Lasts about 2.9 weeks: mixed today, it runs out around 28 Oct.

Mixed vials keep about 3 weeks at 4 °C.

Your vial

The peptide amount is printed on the vial label.

Peptide vial quantity

5 mg10 mg15 mgCustom

−5 mg+

Amount per injection

How much peptide one injection should give.

Desired dose per injection

50 mcg100 mcg250 mcg500 mcgCustom

−250 mcg+= 0.25 mg

Bacteriostatic water

More water makes each unit carry less peptide. It changes the concentration, not the dose.

Use sliderEnter exact amount

2 ml

1 ml2 ml3 mlmost vials5 ml7 ml

Concentration: 2.5 mg/ml

Syringe

Pick the insulin syringe you'll draw with.

Syringe volume

0.3 ml · 30 units0.5 ml · 50 units1 ml · 100 unitsCustom

Plans from ‏99 € a month

Excl. VAT. Seats and a monthly AI allowance included.

For one doctor, start with Solo.

Clinic: 3 seats for ‏299 € a month. Each extra seat ‏99 € a month.

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Solo

For one physician

‏99 €per month

1 doctor
10 protocol drafts a month
AI chat included, fair use
7-day trial

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7 days free with 5 مليون AI tokens.

Clinic

For a clinic team

‏299 €per month

3 seats
Extra seat ‏99 € a month
10 protocol drafts per seat a month
AI chat included, fair use
7-day trial

Start Clinic

7 days free with 5 مليون AI tokens.

Network

For several locations

‏599 €per month

6 seats
Extra seat ‏79 € a month
10 protocol drafts per seat a month
AI chat included, fair use
7-day trial

Start Network

7 days free with 5 مليون AI tokens.

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What is Supercell?

Supercell is practice software for physicians and clinics in longevity medicine. It runs patients, consultations and clinical tools in one place, and a physician reviews and signs every clinical result.

See it with your own cases

We walk you through it on cases like yours.

Book a demo Compare plans

Name	Role	Second step
MCMira Chen	Admin	Passkey
RADr. Robin Alex	Doctor	Authenticator app
DRDr. Dana Ruiz	Doctor	Needs setup	Send reminder
PSDr. Priya Shah	Doctor	Text message
SLSam Lee	Staff	Email code

Who it is for

From question to dose in three steps

Ask

Draft and sign

Dose

How you run the clinic

Every doctor gets a seat

Team and roles

Sign-in and activity log

Your clinic's portal

Your next visit

Visits

Documents

How patients get access

Talk to a licensed doctor

Why clinics switch

For clinical work

For the practice

Where the time comes back

Three tools, one patient context

Plans from ‏99 € a month

Solo

Clinic

Network

What is Supercell?

See it with your own cases

Plans from ‏99 € a month

Solo

Clinic

Network